Product Description: RORγ/DHODH-IN-1 (compound 1404), a deuterium labeled compound, is a dual RORγ and DHODH inhibitor with IC50 values of 9.7 nM and 100 nM, repaectively. RORγ/DHODH-IN-1 blocks the replication of SARS-CoV-2, HCMV, and non-enveloped DNA virus (HAdV5)[1].
Applications: COVID-19-anti-virus
Formula: C23H13D2Cl2F4N3O2
References: [1]Alexandra Herrmann, et al. Orally bioavailable RORγ/DHODH dual host-targeting small molecules with broad-spectrum antiviral activity. Antiviral Res. 2024 Sep 19:231:106008.
CAS Number: 3000567-76-7
Molecular Weight: 514.30
Research Area: Infection
Target: Dihydroorotate Dehydrogenase;DNA/RNA Synthesis;Isotope-Labeled Compounds;ROR