RORγ/DHODH-IN-2, CAS 3000567-45-0

Product Description: RORγ/DHODH-IN-2 (Compound 1311) is an orally active dual inhibitor of RORγ/DHODH with IC50 values of 11.9 nM and 90 nM, respectively. RORγ/DHODH-IN-2 exhibits antiviral activity by inhibiting the activity of SARS-CoV-2, HCMV, HAdV5, and MPXV, with IC50 values of 27 nM, 20 nM, 9.1 nM, and 1.8 nM, respectively[1].

Applications: COVID-19-anti-virus

Formula: C22H16D2ClF4N5O2

References: [1]Herrmann A, et al. Orally Bioavailable RORγ/DHODH Dual Host-Targeting Small Molecules with Broad-Spectrum Antiviral Activity[J]. Antiviral Research, 2024: 106008.

CAS Number: 3000567-45-0

Molecular Weight: 497.87

Research Area: Infection

Target: Dihydroorotate Dehydrogenase;ROR;SARS-CoV

• SKU: MEXHY-169222S-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-169222S-0
• Package Unit: Get quote
• Quantity Unit: STK