Product Description: S-Adenosyl-L-methionine-13C is the 13C labeled S-Adenosyl-L-methionine[1]. S-Adenosyl-L-methionine (S-Adenosyl methionine) is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor. S-Adenosyl-L-methionine is a dietary supplement with potent antidepressant effects, and has the potential for liver disease and osteoarthritis research[2][3][4].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C14 13CH22N6O5S
References: [1]G M Bressa. S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies. Acta Neurol Scand Suppl. 1994;154:7-14./[2]Wadie I Najm, et al. S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495]. BMC Musculoskelet Disord. 2004 Feb 265:6./[3]Shelly C Lu, et al. S-adenosylmethionine in liver health, injury, and cancer. Physiol Rev. 2012 Oct92(4):1515-42.
CAS Number: 74084-24-5
Molecular Weight: 399.43
Research Area: Cancer; Inflammation/Immunology; Neurological Disease
Solubility: 10 mM in DMSO
Target: Apoptosis;Endogenous Metabolite;Isotope-Labeled Compounds
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