(S)-Verapamil-d7 (hydrochloride)

Product Description: (S)-Verapamil-d7 (hydrochloride) is a deuterium labeled (S)-Verapamil hydrochloride. (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells[1][2].

Applications: Cancer-programmed cell death

Formula: C27H32D7ClN2O4

References: [1]Perrotton T, et al. (R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1. J Biol Chem. 2007 Oct 26;282(43):31542-8. Epub 2007 Jul 22./[2]Tannergren C, et al. St John's wort decreases the bioavailability of R- and S-verapamil through induction of the first-pass metabolism. Clin Pharmacol Ther. 2004 Apr;75(4):298-309.

Molecular Weight: 498.11

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;Calcium Channel;Isotope-Labeled Compounds;Leukotriene Receptor

• SKU: MEXHY-135336AS-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-135336AS-1
• Package Unit: 1 mg
• Quantity Unit: STK