Sacubitrilat-d4

Product Description: Sacubitrilat-d4 is the deuterium labeled Sacubitrilat. Sacubitrilat (Desethyl Sacubitril) is an active neprilysin (NEP) inhibitor[1].

Applications: Neuroscience-Neuromodulation

Formula: C22H21D4NO5

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. /[2]Schiering N, et al. Structure of neprilysin in complex with the active metabolite of sacubitril. Sci Rep. 2016 Jun 15;6:27909./[3]Langenickel TH, et al. Single therapeutic and supratherapeutic doses of sacubitril/valsartan (LCZ696) do not affect cardiac repolarization. Eur J Clin Pharmacol. 2016 Aug;72(8):917-24.

Molecular Weight: 387.46

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Isotope-Labeled Compounds;Neprilysin

• SKU: MEXHY-17620S-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-17620S-0
• Package Unit: Get quote
• Quantity Unit: STK