SAR107375-d11 (Tartrate)

Product Description: SAR107375-d11 (Tartrate) is deuterium labeled SAR107375. SAR107375 is a potent and orally active dual thrombin and factor Xa inhibitor, with Ki values of 1 nM and 8 nM for factor Xa and thrombin, respectively[1][2].

Formula: C28H25D11ClN5O11S2

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Jerome Meneyrol, et al. 5-Chlorothiophene-2-carboxylic acid [(S)-2-[2-methyl-3-(2-oxopyrrolidin-1-yl)benzenesulfonylamino]-3-(4-methylpiperazin-1-yl)-3-oxopropyl]amide (SAR107375), a selective and potent orally active dual thrombin and factor Xa inhibitor. J Med Chem. 2013 Dec 12;56(23):9441-56.

Molecular Weight: 729.26

Research Area: Metabolic Disease

Target: Isotope-Labeled Compounds;Thrombin

• SKU: MEXHY-12605S-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-12605S-0
• Package Unit: Get quote
• Quantity Unit: STK