Product Description: Sotalol-d6 (hydrochloride) is a deuterium labeled Sotalol hydrochloride. Sotalol hydrochloride is an orally active, non-selective competitive β-adrenergic receptor blocker. Sotalol hydrochloride is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol hydrochloride blocks β-receptors, and potassium KCNH2 channels[1][2].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C12H15D6ClN2O3S
References: [1]Marta Reyes-Corral, et al. Differential Free Intracellular Calcium Release by Class II Antiarrhythmics in Cancer Cell Lines. J Pharmacol Exp Ther. 2019 Apr;369(1):152-162./[2]Xiaomei Li, et al. Pediatric Dosing of Intravenous Sotalol Based on Body Surface Area in Patients with Arrhythmia. Pediatr Cardiol. 2017 Oct;38(7):1450-1455.
CAS Number: 1246820-85-8
Molecular Weight: 314.86
Compound Purity: 99.0
Research Area: Endocrinology; Cardiovascular Disease
Solubility: 10 mM in DMSO
Target: Adrenergic Receptor;Potassium Channel
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