Product Description: Tyk2-IN-8 is a selective Tyk-2 inhibitor with an IC50 of 5.7 nM for TYK2-JH2. Tyk2-IN-8 inhibits JAK1-JH1 with IC50 of 3.0 nM. Tyk2-IN-8 can be used for the research of autoimmune disease[1].
Applications: COVID-19-immunoregulation
Formula: C20H19D3N8O3
References: [1]Xiangyang Chen, et al. Heterocyclic compounds for inhibiting tyk2 activities. WO2021180072A1.
CAS Number: 2704587-24-4
Molecular Weight: 425.46
Compound Purity: 98.04
Research Area: Inflammation/Immunology
Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 80°C)