TYK2 JH2-IN-1-d3, CAS 2376999-19-6

Product Description: TYK2 JH2-IN-1-d3 is the a deuterated, orally active and selective TYK2 inhibitor (compound 4h), targeting to JH2 domain (IC50=0.1 nM)[1].

Applications: Cancer-Kinase/protease

Formula: C24H21D3FN9O3

References: [1]Xiao Z, et al. Structure-activity relationship study of central pyridine-derived TYK2 JH2 inhibitors: Optimization of the PK profile through C4' and C6 variations. Bioorg Med Chem Lett. 2023 Jul 15;91:129373.

CAS Number: 2376999-19-6

Molecular Weight: 508.52

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: JAK

• SKU: MEXHY-149892S-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-149892S-1
• Package Unit: 1 mg
• Quantity Unit: STK