(Z)-10-Hydroxynortriptyline-d3

Product Description: (Z)-10-Hydroxynortriptyline-d3 is the deuterium labeled (Z)-10-Hydroxynortriptyline (HY-100646A). (Z)-10-Hydroxynortriptyline is a metabolite of Nortriptyline (HY-118620). Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C19H18D3NO

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22(4):371-8.

Molecular Weight: 282.40

Compound Purity: 99.0

Research Area: Neurological Disease

Solubility: 10 mM in DMSO/DMF : ≥ 30mg/mL/DMSO : ≥ 10mg/mL/Ethanol : ≥ 5mg/mL

Target: Drug Metabolite

• SKU: MEXHY-100646AS-100UG
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-100646AS-100UG
• Package Unit: 100 μg
• Quantity Unit: STK