244cis, CAS 2956402-64-3

Product Description: 244cis, a piperazine-containing ionizable cationic lipid, has been used to generate lipid nanoparticles (LNPs). LNPs containing 244cis and coated with mRNA reporter gene were specifically accumulated in mouse lungs compared with LNPs containing SM-102. Induces a decrease in serum chemokine (C-C motif) ligand 2 (CCL2) levels[1].

Applications: Metabolism-sugar/lipid metabolism

Formula: C60H111N3O6

References: [1]Kim M, et al. Novel piperazine-based ionizable lipid nanoparticles allow the repeated dose of mRNA to fibrotic lungs with improved potency and safety. Bioeng Transl Med. 2023 May 28;8(6):e10556.

CAS Number: 2956402-64-3

Molecular Weight: 970.54

Compound Purity: 96.70

Research Area: Others

Solubility: 10 mM in DMSO

Target: Liposome

• SKU: MEXHY-160552-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-160552-1
• Package Unit: 1 mg (25,76 mM * 40 μL in Ethanol)
• Quantity Unit: STK