Product Description: C12-113 is a lipidoid delivery agent that can be used to transfect siRNA into cells. C12-113 can also be combined with other lipids to form lipid nanoparticles (LNPs) for the delivery of mRNA encoding the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in mice[1][2].
Applications: COVID-19-anti-virus
Formula: C53H111N3O4
References: [1]Li J, Song J S, et al. YY1 regulates melanocyte development and function by cooperating with MITF[J]. PLoS genetics, 2012, 8(5): e1002688.
CAS Number: 1220890-27-6
Molecular Weight: 854.47
Research Area: Infection; Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: Liposome