Calcium 2-hydroxypropanoate (pentahydrate), CAS 5743-47-5

Product Description: Calcium 2-hydroxypropanoate (pentahydrate) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Calcium 2-hydroxypropanoate (pentahydrate) is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Calcium 2-hydroxypropanoate (pentahydrate) is an oncometabolite and has immune protective role of lactate in anti-tumor immunity[1][2].

Formula: C3H6O3.0.5Ca.2.5H2O

References: [1]Lucia Longhitano, et al. Lactate Rewrites the Metabolic Reprogramming of Uveal Melanoma Cells and Induces Quiescence Phenotype. Int J Mol Sci. 2022 Dec 20;24(1):24. /[2]Qiang Feng, et al. Lactate increases stemness of CD8 + T cells to augment anti-tumor immunity. Nat Commun. 2022 Sep 6;13(1):4981.

CAS Number: 5743-47-5

Molecular Weight: 155.17

Research Area: Cancer; Metabolic Disease; Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Endogenous Metabolite

• SKU: MEXHY-B2227D-100G
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-B2227D-100G
• Package Unit: 100 g
• Quantity Unit: STK