Product Description: Dios-Arg diTFA, a cationic lipid with an arginine-bearing headgroup, shows obvious double bond proton signals at around 5.2-5.3 ppm. Dios-Arg diTFA is used, coupled to DOPE, to bind siRNA and plasmid to for cationic LNPs for intracellular transport[1][2].
Applications: Cancer-programmed cell death
Formula: C43H67F6N5O9
References: [1]Ruilong Sheng, et al. Cationic Nanoparticles Assembled from Natural-Based Steroid Lipid for Improved Intracellular Transport of siRNA and pDNA. Nanomaterials (Basel). 2016 Apr 13;6(4):69./[2]Ruilong Sheng, et al. Skeleton-Controlled pDNA Delivery of Renewable Steroid-Based Cationic Lipids, the Endocytosis Pathway Analysis and Intracellular Localization. Int J Mol Sci. 2018 Jan 26;19(2):369.
CAS Number: 1807353-31-6
Molecular Weight: 912.01
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Liposome
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