Shelf life (days): 1460.0
Formulation: A solid
Formal Name: glycyl-L-isoleucyl-L-cysteinyl-L-alanyl-L-cysteinyl-L-arginyl-L-arginyl-L-arginyl-L-phenylalanyl-L-cysteinyl-L-prolyl-L-asparaginyl-L-seryl-L-a-glutamyl-L-arginyl-L-phenylalanyl-L-serylglycyl-L-tyrosyl-L-cysteinyl-L-arginyl-L-valyl-L-asparaginylglycyl-L-alanyl-L-arginyl-L-tyrosyl-L-valyl-L-arginyl-L-cysteinyl-L-cysteinyl-L-seryl-L-arginyl-L-arginine, trifluoroacetate salt
Amino Acids: GICACRRRFCPNSERFSGYCRVNGARYVRCCSRR-OH
Purity: ≥95%
Formula Markup: C163H265N63O44S6 / XCF3COOH
Formula Weight: 4003.7
Notes: An a-defensin peptide; active against C. albicans at 10 µg/ml; induces leakage of high molecular weight dextrans and low molecular weight reporters in combination with NP-1, NP-2, NP-3B, NP-4, and NP-5 in E. coli membrane mimics; inhibits phagocytosis in primary mouse macrophages in a concentration-dependent manner; induces histamine secretion in primary rat mast cells (EC50 = 70 nM); inhibits corticotropin-induced corticosterone production but does not decrease basal corticosterone levels in primary rat adrenal cells (IC50 = 33 pM)
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