Product Description: Hyaluronidase (human recombinant) (Hylenex; Vorhyaluronidase alfa; rHuPH 20) is an enzyme that catalyzes the degradation of hyaluronic acid. Hyaluronidase (human recombinant) is used to improve the absorption and dispersal of parenteral fluids, medications, and contrast media[1].
Applications: Cancer-programmed cell death
Formula: N/A
References: [1]E J Menzel, et al. Hyaluronidase and its substrate hyaluronan: biochemistry, biological activities and therapeutic uses. Cancer Lett. 1998 Sep 11;131(1):3-11./[2]Evison M, et al. Human recombinant hyaluronidase (Cumulase) improves intracytoplasmic sperm injection survival and fertilization rates. Reprod Biomed Online. 2009 Jun;18(6):811-4. /[3]Gao X, et al. Mechanistic Modeling of the Effect of Recombinant Human Hyaluronidase (rHuPH20) on Subcutaneous Delivery of Cetuximab in Rats. Pharm Res. 2022 Aug;39(8):1867-1880.
CAS Number: 37326-33-3
Molecular Weight: N/A
Research Area: cancer
Solubility: 10 mM in DMSO
Target: Biochemical Assay Reagents;Others
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