Formal Name: eicosanoic acid, (2R)-2-hydroxy-3-(phosphonooxy)propyl ester, monosodium salt
Purity: ≥95%
Formula Markup: C23H46O7P / Na
Formula Weight: 488.6
Notes: 1-Arachidoyl-2-hydroxy-sn-glycero-3-PA (1-arachidoyl LPA) is an agonist of lysophosphatidic acid receptor 1 (LPA1) and a glycerophospholipid containing arachidic acid (Item Nos. 9000339 / 21906) at the sn-1 position.{69580} It induces calcium mobilization in primary human lung fibroblasts (EC50 = 3.6 µM), which endogenously express LPA1 but not LPA2-LPA6. 1-Arachidoyl LPA (2.5 µM) also binds to the ligand-binding domain of peroxisome proliferator-activated receptor γ (PPARγ) in a cell-free assay.{15069} It has been found in human urine.{69581}