(1R,9S)-(–)-β-Hydrastine, CAS 118-08-1

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: (3S)-6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone

Purity: ≥98%

Formula Markup: C21H21NO6

Formula Weight: 383.4

CAS Number: 118-08-1

Notes: (1R,9S)-(–)-β-Hydrastine is an enantiomer of the alkaloid hydrastine that inhibits dopamine biosynthesis (IC50 = 20.7 µM in PC12 cells) by inhibiting tyrosine hydroxylase activity.{38222,38223} It inhibits dopamine release with an IC50 value of 66.5 µM in the presence of high extracellular K+ levels. It also inhibits L-type and caffeine-activated store-operated Ca2+ channels and prevents Ca2+ leakage from intracellular stores.{38224,38225}

• SKU: CAY22363-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 22363-5
• Package Unit: 5 mg
• Quantity Unit: STK