Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 2,3-dihydro-N-methyl-N-[2-oxo-2-[(2,3,4-trifluorophenyl)amino]ethyl]-1,4-benzodioxin-6-carboxamide
Purity: ≥98%
Formula Markup: C18H15F3N2O4
Formula Weight: 380.317989
CAS Number: 870768-70-0
Notes: An agonist of LXRα and LXRβ; induces transactivation of LXRα and LXRβ in reporter assays using HEK293T cells (EC50s = 0.15 and 0.53 µM, respectively); increases protein levels of ABCG1 and ABCA1 in RAW 264.7 and THP-1 cells at 1 or 10 µM; induces cholesterol efflux and reduces oxidized LDL-induced lipid accumulation in RAW 264.7 cells at 1 or 10 µM