Shelf life (days): 1460.0
Formulation: A solid
Formal Name: (3S)-3-hydroxy-N-[(2S)-2-hydroxy-1-oxo-2-[(2R,5R,6R)-tetrahydro-2-hydroxy-6-methyl-5-[(2S)-2-methylbutyl]-2H-pyran-2-yl]propyl]-L-leucyl-(3R)-hexahydro-3-pyridazinecarbonyl-N-hydroxy-L-alanylglycyl-(3S)-hexahydro-3-pyridazinecarbonyl-N-hydroxy-D-alanine, (6?13)-lactone
Purity: ≥95%
Formula Markup: C38H64N8O13
Formula Weight: 841.0
CAS Number: 125228-51-5
Notes: L-156,602 is an antagonist of the complement component 5A (C5a) receptor (IC50 = 1.7 µg/L in a radioligand binding assay using neutrophil membranes).{38590} It is also a cyclic depsipeptide antibiotic that is active against Gram-positive bacteria.{38591} L-156,602 has anti-inflammatory activity in mice, decreasing inflammation induced by muramyl dipeptide (MDP) when administered at a dose of 0.5 mg/kg and by concanavalin A (Item No. 14951) at doses of 0.25 and 0.5 mg/kg.{38592}
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