Losartan-d4, CAS 1030937-27-9

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl-2,3,5,6-d4]methyl]-1H-imidazole-5-methanol

Purity: ≥99% deuterated forms (d1-d4)

Formula Markup: C22H19ClD4N6O

Formula Weight: 426.9

CAS Number: 1030937-27-9

Notes: Losartan-d4 is intended for use as an internal standard for the quantification of losartan (potassium salt) (Item No. 10006594) by GC- or LC-MS. Losartan is an antagonist of the angiotensin (AT) II receptor subtype AT1 with a Ki value of 5-20 nM.{12997} It has an attenuating effect on vein graft atherosclerosis in rabbits and effectively reduces arterial blood pressure in rats.{12998,13089} Formulations containing losartan have been used to control hypertension while protecting renal function.{12996}

• SKU: CAY22567-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 22567-1
• Package Unit: 1 mg
• Quantity Unit: STK
• Application: GC-MS, LC-MS, Isotopenmarkierung