LXR-623, CAS 875787-07-8

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole

Purity: ≥98%

Formula Markup: C21H12ClF5N2

Formula Weight: 422.8

CAS Number: 875787-07-8

Notes: LXR-623 is a liver X receptor (LXR) modulator that acts as a partial agonist at LXRα and a full agonist at LXRβ (IC50s = 179 and 24 nM, respectively).{33455,32907} It is orally bioavailable and readily passes the blood-brain barrier.{33455,32907,32909} LXR-623 is anti-atherogenic in animal models of atherosclerosis, showing synergistic effects when combined with simvastatin (Item Nos. 10010344 / 10010345).{33455,33456,32907}

• SKU: CAY21117-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 21117-1
• Package Unit: 1 mg
• Quantity Unit: STK