MM-54 (trifluoroacetate salt)

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: L-cysteinyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-cysteinyl-L-lysyl-L-histidyl-L-cysteinyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-cysteine, cyclic (1?6),(9?14)-bis(disulfide), trifluoroacetate salt

Amino Acids: cyclic[CRPRLC]-KH-cyclic[CRPRLC]-OH

Purity: ≥95%

Formula Markup: C70H121N29O15S4 / XCF3COOH

Formula Weight: 1737.1602

Notes: A peptide antagonist of APJ (Ki = 82 nM); inhibits apelin-induced increases in stem cell and tumorsphere numbers and the percentage of stem cells with aldehyde dehydrogenase (ALDH) activity, a marker of stem cells, in patient-derived glioblastoma spheroids at 100 µM; decreases tumor volume in a PDX mouse model of glioblastoma at 2 mg/kg twice per week

• SKU: CAY42401-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42401-1
• Package Unit: 1 mg
• Quantity Unit: STK