Notes: Picotamide is an antiplatelet drug that inhibits both thromboxane A2 (TXA2) receptors (Kd = 325 nM) and TXA2 synthase.{34208,34210} It significantly inhibits basal and lipopolysaccharide-stimulated TXA2 synthesis by rat peritoneal macrophages when used at 0.5 mM.{34209} Formulations containing picotamide have potential applications in the reduction of peripheral artery disease in patients with diabetes.{34208}