Riluzole-13C,15N2, CAS 1215552-03-6

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 6-(trifluoromethoxy)benzo[d]thiazol-2-13C-3-15N-2-amine-15N

Purity: ≥98%

Formula Markup: C7[13C]H5F3[15N]2OS

Formula Weight: 237.2

CAS Number: 1215552-03-6

Notes: Riluzole-13C,15N2 is intended for use as an internal standard for the quantification of riluzole (Item No. 14577) by GC- or LC-MS. Riluzole is a benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na+ channels (ED50 = 2.3 μM).{22851} Riluzole suppresses glutamate-induced seizures in rats at an ED50 value of 3.2 mg/kg and displays neuroprotective effects in hypoxic animals at an ED50 value of 4 mg/kg. Formulations containing riluzole have been explored as therapeutics for slowing disease progression of amyotrophic lateral sclerosis.

• SKU: CAY25361
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 25361-1
• Package Unit: 1 mg
• Quantity Unit: STK
• Application: GC-MS, LC-MS, Isotopenmarkierung