Shelf life (days): 1460.0
Formulation: A solid
Formal Name: (3-endo)-8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol
Purity: ≥98%
Formula Markup: C28H31NO
Formula Weight: 397.562
CAS Number: 322473-89-2
Notes: A NOP receptor agonist; induces [35S]GTPγS binding to CHO membranes expressing recombinant human NOP receptors (EC50 = 12 nM); increases time spent in the open arms and number of open arm entries in an elevated plus maze in rats at 10 mg/kg; increases drinking in the Vogel punished drinking task in rats at 3, 10, or 30 mg/kg; reduces the number of vocalizations in a guinea pig pup model of separation-induced anxiety at 0.3, 1, or 3 mg/kg; decreases the number of coughs in a guinea pig model of capsaicin-induced coughing (ED50 = 0.07 mg/kg)