WAY-181187, CAS 554403-49-5

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 1-[(6-chloroimidazo[2,1-b]thiazol-5-yl)sulfonyl]-1H-indole-3-ethanamine

Purity: ≥98%

Formula Markup: C15H13ClN4O2S2

Formula Weight: 380.87418

CAS Number: 554403-49-5

Notes: A 5-HT6 receptor agonist; increases intracellular cAMP levels in HeLa cells expressing 5-HT6 (EC50 = 6.5 nM); selectively binds to 5-HT6 over 5-HT2B, 5-HT2C, and 5-HT7 (Kis = 2,458, 124, and 679 nM, respectively); selective for 5-HT6 over a panel of 31 receptors and ion channels at 100 nM; increases extracellular GABA levels in the rat frontal cortex at 10 mg/kg; reduces schedule-induced polydipsia, an adjunctive model of compulsive disorder, in rats at 178 mg/kg; has antidepressant-like activity in rats at 17 mg/kg and anxiolytic-like activity in rats at 10 and 17 mg/kg

• SKU: CAY23461-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 23461-25
• Package Unit: 25 mg
• Quantity Unit: STK