Shelf life (days): 1460.0
Formulation: A solid
Formal Name: a-[4-[[(2S,3R,4E)-3-hydroxy-2-[(1-oxohexadecyl)amino]-4-octadecen-1-yl]oxy]-1,4-dioxobutyl]-?-methoxy-poly(oxy-1,2-ethanediyl)
Purity: ≥90%
Formula Markup: (C2H4O)nC39H73NO6
Formula Weight: 0.0
CAS Number: 212116-78-4
Notes: A PEGylated form of C16 ceramide; has been used in the generation of microspheres, LNPs, and liposomes for the delivery of small molecules, mRNA, and plasmid DNA in vitro and in vivo; liposomes containing C16 ceramide-mPEG(2000) with a stearylated-INF7 and have been used to transfect plasmid DNA into MFLM-4 cells; microspheres containing C16 ceramide-mPEG(2000) and encapsulating oxaliplatin increase survival and decrease the number of small intestine, colon, and cecum polyps in an Apc+/Minz spontaneous colorectal adenoma mouse model