C8 Ceramide-mPEG(2000), CAS 212116-76-2

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: a-[4-[[(2S,3R,4E)-3-hydroxy-2-[(1-oxooctyl)amino]-4-octadecen-1-yl]oxy]-1,4-dioxobutyl]-methoxy-poly(oxy-1,2-ethanediyl)

Purity: ≥90%

Formula Markup: (C2H4O)nC31H57NO6

Formula Weight: 0.0

CAS Number: 212116-76-2

Notes: A PEGylated form of C8 ceramide; has been used in the generation of lipoplexes and lipid particles for the delivery of plasmid DNA and siRNA in vitro and in vivo; lipid particles encapsulating plasmid DNA and containing C8 MPEG(2000) ceramide have a higher transfection efficiency than those containing C14- or C20 MPEG(2000) ceramide in BHK cells; lipoplexes containing C8 MPEG(2000) ceramide and encapsulating siRNAs targeting HPV E7 peptide and Mcl-1 induce apoptosis in Ca Ski and SiHa cervical cancer cells; intravaginal administration of lipoplexes containing C8 MPEG(2000) ceramide accumulate in vaginal tissue in mice

• SKU: CAY41954-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 41954-1
• Package Unit: 1 mg
• Quantity Unit: STK