Shelf life (days): 1460.0
Formulation: A solid
Formal Name: N-((7S,10S,13S,16S,19S,22S,25S,28S)-1,34-diamino-7-carbamoyl-10,13,16,19,22,25-hexakis(4-guanidinobutyl)-1,34-diimino-9,12,15,18,21,24,27-heptaoxo-2,8,11,14,17,20,23,26,33-nonaazatetratriacontan-28-yl)stearamide, trifluoroacetate salt
Purity: ≥95%
Formula Markup: C74H149N33O9 / XCF3COOH
Formula Weight: 1645.2
Notes: A stearic acid-conjugated cell-penetrating peptide; has been used in the generation of liposomes for plasmid DNA or siRNA delivery in vitro; liposomes containing stearyl-(homoarginine)8 and in complex with plasmid DNA enter NIH3T3 cells via the endocytosis pathway; liposomes containing a high density, but not a low density, of stearyl-(homoarginine)8 and encapsulating plasmid DNA increase plasmid DNA expression without being degraded by lysosomes in NIH3T3 cells; stearyl-(homoarginine)8-containing liposomes encapsulating siRNA targeting mRNA encoding GAPDH decrease GAPDH levels in primary human aortic smooth muscle cells
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