Lipid PPz-2R1, CAS 2832061-40-0

Shelf life (days): 365.0

Formulation: A solution in ethanol

Formal Name: piperazine-1,4-diylbis(hexane-6,1-diyl) bis(2-hexyldecanoate)

Purity: ≥98%

Formula Markup: C48H94N2O4

Formula Weight: 763.29

CAS Number: 2832061-40-0

Notes: An ionizable cationic lipid; has been used in the generation of LNPs for the delivery of mRNA in vitro and in vivo; LNPs containing lipid PPz-2R1 and encapsulating an mRNA reporter selectively accumulate in lungs over the heart, liver, spleen, and kidneys in mice; LNPs containing lipid PPz-2R1 and encapsulating PTEN mRNA increase PTEN protein levels in PTEN-deficient LLC cells; lipid PPz-2R1-containing LNPs encapsulating PTEN mRNA reduce tumor growth in an orthotopic murine LLC model when administered alone or in combination with an anti-PD-1 antibody

• SKU: CAY43160-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 43160-5
• Package Unit: 5 mg
• Quantity Unit: STK