Shelf life (days): 730.0
Formulation: A solution in ethanol
Formal Name: 5Z,9Z,12Z-octadecatrienoic acid, methyl ester
Purity: ≥98%
Formula Markup: C19H32O2
Formula Weight: 292.5
CAS Number: 38406-57-4
Notes: Pinolenic acid is a polyunsaturated fatty acid found in Korean pine (Pinus orientalis) and maritime pine (Pinus pinaster) seed oils. Both oils have been found to have lipid-lowering properties. A diet containing maritime pine seed oil (MPSO) lowered HDL and ApoA-I levels in transgenic mice expressing human ApoA-I. MPSO was found to diminish cholesterol efflux in vitro.{14273} Korean pine seed oil supplements may help in obesity by reduction of appetite. People taking this oil had an increase in the satiety hormones CCK and GLP-1 and a reduced desire to eat.{14280} The activity of the oil is attributed to pinolenic acid. Due to the non-methylene-interrupted double bond at the Δ5 position, pinolenic acid is not converted to arachidonic acid metabolically. Pinoleic acid can reduce arachidonic acid levels in the phosphatidylinositol fraction of Hep-G2 cells from 15.9% to 7.0%.{8724} Pinolenic acid methyl ester is a neutral, more lipophilic form of the free acid.
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