(S)-C12-200, CAS 1226552-44-8

(S)-C12-200, CAS 1226552-44-8
SKU
CAY38885-25
Packaging Unit
25 mg
Manufacturer
Cayman Chemical

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Shelf life (days): 365.0

Formulation: A solution in ethanol

Formal Name: 1,1'-[[2-[4-[2-[[2-[bis[(2S)-2-hydroxydodecyl]amino]ethyl][(2S)-2-hydroxydodecyl]amino]ethyl]-1-piperazinyl]ethyl]imino]bis-2-dodecanol

Purity: ≥98%

Formula Markup: C70H145N5O5

Formula Weight: 1137.0

CAS Number: 1226552-44-8

Notes: (S)-C12-200 is an ionizable cationic lipid (pKa = 7.12) and an isomer of C12-200 (Item No. 36699).{66651} It has been used in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo. Intravenous administration of LNPs containing (S)-C12-200 and encapsulating mRNA encoding Cre recombinase increase the percentage of tdTomato+ hepatocytes, endothelial cells, and Kupffer cells in the livers of Ai14 mice greater than (R)-C12-200-containing and Cre mRNA-encapsulating LNPs.
More Information
SKU CAY38885-25
Manufacturer Cayman Chemical
Manufacturer SKU 38885-25
Package Unit 25 mg
Quantity Unit STK
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