Product Description: 3,6-Dihydroxyflavone is an anti-cancer agent. 3,6-Dihydroxyflavone dose- and time-dependently decreases cell viability and induces apoptosis by activating caspase cascade, cleaving poly (ADP-ribose) polymerase (PARP). 3,6-Dihydroxyflavone increases intracellular oxidative stress and lipid peroxidation[1].
Applications: Cancer-programmed cell death
Formula: C15H10O4
References: [1]Chang H, et al. 3,6-Dihydroxyflavone induces apoptosis in leukemia HL-60 cell via reactive oxygen species-mediated p38 MAPK/JNK pathway. Eur J Pharmacol. 2010;648(1-3):31-38.
CAS Number: 108238-41-1
Molecular Weight: 254.241
Compound Purity: 99.45
Research Area: Cancer
Solubility: DMSO : 66.67 mg/mL (ultrasonic)
Target: Apoptosis