5,7-Dihydroxychromone, CAS 31721-94-5

Product Description: 5,7-Dihydroxychromone, the extract of Cudrania tricuspidata, activates Nrf2/ARE signal and exerts neuroprotective effects against 6-hydroxydopamine (6-OHDA)-induced oxidative stress and apoptosis. 5,7-Dihydroxychromone inhibits the expression of activated caspase-3 and caspase-9 and cleaved PARP in 6-OHDA-induced SH-SY5Y cells[1].

Applications: Neuroscience-Neurodegeneration

Formula: C9H6O4

References: [1]Kim DW, et al. Neuroprotection against 6-OHDA-induced oxidative stress and apoptosis in SH-SY5Y cells by 5,7-Dihydroxychromone: Activation of the Nrf2/ARE pathway. Life Sci. 2015 Jun 1;130:25-30.

CAS Number: 31721-94-5

Molecular Weight: 178.143

Compound Purity: 99.94

Research Area: Neurological Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Arenavirus;Caspase;Keap1-Nrf2;PARP

• SKU: MEXHY-N1970-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N1970-10.1
• Package Unit: 10mM/1mL
• Quantity Unit: STK