Product Description: α-Ionone (alpha-Ionone) is an activator of the olfactory receptor OR10A6. α-Ionone induces apoptosis by activating OR10A6 and increasing the phosphorylation of the LATS-YAP-TAZ signaling axis in the Hippo pathway. α-Ionone can inhibit tumor formation both in vivo and in vitro[1].
Formula: C13H20O
References: [1]Yoon YE, et al. A Food Odorant, α-Ionone, Inhibits Skin Cancer Tumorigenesis by Activation of OR10A6. Mol Nutr Food Res. 2024 Aug;68(15):e2400085./[2]Ozgen U, et al. A new sulfated alpha-ionone glycoside from Sonchus erzincanicus Matthews. Molecules. 2010 Apr 12;15(4):2593-9.
CAS Number: 127-41-3
Molecular Weight: 192.30
Compound Purity: 94.30
Research Area: Cancer
Solubility: DMSO : 200 mg/mL (ultrasonic)
Target: Hippo (MST);YAP