Product Description: (-)-Alkannin, found in Alkanna tinctoria, is used as a food coloring. (-)-Alkannin shows anticancer activity, arrests cell cycle, and induces apoptosis. (-)-Alkannin improves hepatic inflammation in a Rho-kinase pathway[1][2][3].
Applications: COVID-19-immunoregulation
Formula: C16H16O5
References: [1]Hosokawa Y, et al. Alkannin inhibits CCL3 and CCL5 production in human periodontal ligament cells. Cell Biol Int. 2016 Dec;40(12):1380-1385./[2]Huu Tung N, et al. Naphthoquinone components from Alkanna tinctoria (L.) Tausch show significant antiproliferative effects on human colorectal cancer cells. Phytother Res. 2013 Jan;27(1):66-70./[3]Xue W, et al. Alkannin Inhibited Hepatic Inflammation in Diabetic Db/Db Mice. Cell Physiol Biochem. 2018;45(6):2461-2470.
CAS Number: 517-88-4
Molecular Weight: 288.30
Compound Purity: 99.88
Research Area: Cancer; Inflammation/Immunology
Solubility: DMSO : 33.33 mg/mL (ultrasonic)
Target: Apoptosis
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