Atraric acid, CAS 4707-47-5

Product Description: Atraric acid (Methyl atrarate) is a specific androgen receptor (AR) antagonist with anti-inflammatory and anticancer effects. Atraric acid represses the expression of the endogenous prostate specific antigen gene in both LNCaP and C4-2 cells. Atraric acid can also inhibit the synthesis of NO and cytokine, and suppress the MAPK-NFκB signaling pathway. Atraric acid can be used to research prostate diseases and inflammatory diseases[1][2].

Applications: COVID-19-immunoregulation

Formula: C10H12O4

References: [1]Roell D, Baniahmad A. The natural compounds atraric acid and N-butylbenzene-sulfonamide as antagonists of the human androgen receptor and inhibitors of prostate cancer cell growth. Mol Cell Endocrinol. 2011 Jan 30;332(1-2):1-8./[2]Papaioannou M, et al. The natural compound atraric acid is an antagonist of the human androgen receptor inhibiting cellular invasiveness and prostate cancer cell growth. J Cell Mol Med. 2009 Aug;13(8B):2210-2223.

CAS Number: 4707-47-5

Molecular Weight: 196.202

Compound Purity: 99.94

Research Area: Cancer; Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Androgen Receptor;NF-κB;NO Synthase;p38 MAPK

• SKU: MEXHY-N2908-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N2908-10.1
• Package Unit: 10mM/1mL
• Quantity Unit: STK