Product Description: Cynandione A is an acetophenone that can be isolated from Cynanchum Wilfordii Radix. Cynandione A protects hepatocytes and cortical neurons from toxicity and improves neurological deficits in a rat model of cerebral ischemia. On the other hand, cynandione A has significant anti-inflammatory effects and inhibits inflammation by activating macrophage α7 nAChR and IL-10 expression[1].
Formula: C16H14O6
References: [1]Han Q Q, et al. Cynandione A and PHA-543613 inhibit inflammation and stimulate macrophageal IL-10 expression following α7 nAChR activation[J]. Biochemical Pharmacology, 2021, 190: 114600.
CAS Number: 168706-29-4
Molecular Weight: 302.28
Research Area: Inflammation/Immunology
Target: Interleukin Related;nAChR