Derrone, CAS 76166-59-1

Product Description: Derrone, a prenylated isoflavones, is an Aurora kinase inhibitor, with IC50 values of 6 and 22.3 μM against Aurora B and Aurora A, respectively. Derrone shows anti-tumor activity[1][2].

Applications: Cancer-Kinase/protease

Formula: C20H16O5

References: [1]Hoang NT, et al. In Vitro Characterization of Derrone as an Aurora Kinase Inhibitor. Biol Pharm Bull. 2016 Jun 1;39(6):935-45./[2]Kang MJ, et al. Derrone induces autophagic cell death through induction of ROS and ERK in A549 cells. PLoS One. 2019 Jun 19;14(6):e0218659.

CAS Number: 76166-59-1

Molecular Weight: 336.34

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Aurora Kinase;PERK;Reactive Oxygen Species

• SKU: MEXHY-N3737-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N3737-1
• Package Unit: 1 mg
• Quantity Unit: STK