Glaucocalyxin B, CAS 80508-81-2

Product Description: Glaucocalyxin B is an ent kaurane diterpenoid isolated from the Chinese traditional medicine Rabdosia japonica with anticancer and antitumor activity; decreases the growth of HL-60 cells with an IC50 of approximately 5.86 μM at 24 h.

Applications: Cancer-Kinase/protease

Formula: C22H30O5

References: [1]Yang WH, et al. Glaucocalyxin A and B-induced cell death is related to GSH perturbation in human leukemia HL-60 cells. Anticancer Agents Med Chem. 2013 Oct;13(8):1280-90./[2]Pan Y, et al. Glaucocalyxin B induces apoptosis and autophagy in human cervical cancer cells. Mol Med Rep. 2016 Aug;14(2):1751-5./[3]Gan P, et al. Anti-inflammatory effects of glaucocalyxin B in microglia cells. J Pharmacol Sci. 2015 May;128(1):35-46.

CAS Number: 80508-81-2

Molecular Weight: 374.47

Compound Purity: 99.65

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Autophagy

• SKU: MEXHY-N2113-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N2113-10
• Package Unit: 10 mg
• Quantity Unit: STK