(−)-Gossypol (acetate), CAS 866541-93-7

(−)-Gossypol (acetate), CAS 866541-93-7
SKU
CAY42421-25
Packaging Unit
25 mg
Manufacturer
Cayman Chemical

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Shelf life (days): 1460.0

Formulation: A solid

Formal Name: (2R)-1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-[2,2'-binaphthalene]-8,8'-dicarboxaldehyde, compd. with acetic acid (1:1)

Purity: ≥98%

Formula Markup: C30H30O8 / C2H4O2

Formula Weight: 578.614

CAS Number: 866541-93-7

Notes: A polyphenol with spermicidal and anticancer activities; induces complete immobilization of isolated human sperm within 3 minutes at 5 mg/ml; inhibits Bcl-2, Bcl-xL, and Mcl-1 (Kis = 0.32, 0.48, and 0.18 µM, respectively); induces apoptosis in patient-derived B-CLL cells at 20 µM; induces tumor regression in an RL DLBCL mouse xenograft model at 35 mg/kg in combination with rituximab and cyclophosphamide
More Information
SKU CAY42421-25
Manufacturer Cayman Chemical
Manufacturer SKU 42421-25
Package Unit 25 mg
Quantity Unit STK
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