Product Description: Hirsutine, an indole alkaloid of Uncaria rhynchophylla, exhibits anti-cancer activity. Hirsutine induces apoptosis and is a potent Dengue virus inhibitor exhibiting low cytotoxicity[1][2][3].
Applications: COVID-19-anti-virus
Formula: C22H28N2O3
References: [1]Hishiki T, et al. Hirsutine, an Indole Alkaloid of Uncaria rhynchophylla, Inhibits Late Step in Dengue Virus Lifecycle. Front Microbiol. 2017 Aug 30;8:1674./[2]Huang QW, et al. [Hirsutine induces apoptosis of human breast cancer MDA-MB-231 cells through mitochondrial pathway]. Sheng Li Xue Bao. 2018 Feb 25;70(1):40-46./[3]Zhang R, et al. Hirsutine induces mPTP-dependent apoptosis through ROCK1/PTEN/PI3K/GSK3β pathway in human lung cancer cells. Cell Death Dis. 2018 May 22;9(6):598.
CAS Number: 7729-23-9
Molecular Weight: 368.47
Compound Purity: 99.46
Research Area: Cancer; Infection
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Apoptosis;Dengue virus;Flavivirus
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