Moracin O, CAS 123702-97-6

Product Description: Moracin O is a 2-arylbenzofuran isolated from the Morus alba Linn. . Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin O reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin O has neuroprotective and anti-inflammatory effects[1][2][3].

Applications: COVID-19-immunoregulation

Formula: C19H18O5

References: [1]Hak Ju Lee, et al. Inhibitory effect of 2-arylbenzofurans from the Mori Cortex Radicis (Moraceae) on oxygen glucose deprivation (OGD)-induced cell death of SH-SY5Y cells. Arch Pharm Res. 2011 Aug;34(8):1373-80./[2]Yan Xia, et al. HIF-1α inhibitors: synthesis and biological evaluation of novel moracin O and P analogues. Eur J Med Chem. 2011 Jun;46(6):2386-96./[3]Besse Hardianti, et al. Anti-inflammatory compounds moracin O and P from Morus alba Linn. (Sohakuhi) target the NF‑κB pathway. Mol Med Rep. 2020 Dec;22(6):5385-5391.

CAS Number: 123702-97-6

Molecular Weight: 326.34

Compound Purity: 99.95

Research Area: Cancer; Inflammation/Immunology; Neurological Disease

Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

Target: HIF/HIF Prolyl-Hydroxylase;Reactive Oxygen Species

• SKU: MEXHY-N3244-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N3244-1
• Package Unit: 1mg
• Quantity Unit: STK