Product Description: Naringenin chalcone is an intermediate in flavonol biosynthesis and is spontaneously metabolized into naringenin (NAR) by chalcone isomerase. Naringenin chalcone is an orally active anti-inflammatory and antiallergic agent[1].
Applications: COVID-19-immunoregulation
Formula: C15H12O5
References: [1]Escribano-Ferrer E, et al. In Vivo Anti-inflammatory and Antiallergic Activity of Pure Naringenin, Naringenin Chalcone, and Quercetin in Mice.J Nat Prod. 2019 Feb 22;82(2):177-182./[2]Iwamura C, Shinoda K, Yoshimura M, Watanabe Y, Obata A, Nakayama T. Naringenin chalcone suppresses allergic asthma by inhibiting the type-2 function of CD4 T cells. Allergol Int. 2010;59(1):67-73. /[3]Hirai S, Kim YI, Goto T, et al. Inhibitory effect of naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophages. Life Sci. 2007;81(16):1272-1279.
CAS Number: 73692-50-9
Molecular Weight: 272.25
Compound Purity: 99.29
Research Area: Inflammation/Immunology
Solubility: DMSO : 50 mg/mL (ultrasonic)/Methanol : ≥ 25 mg/mL
Target: Others
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