1-Acetyl-DHAP, CAS 2267338-53-2

Product Description: 1-Acetyl-DHA (Compound 7) is a substrate of the phosphotriesterase homology protein (PHP) and can be hydrolyzed by PHP with a kcat/km value of 100 M-1s-1. The level of 1-Acetyl-DHA is regulated by mTORC1 and is negatively correlated with the nuclear acetate level. 1-Acetyl-DHA plays an important role in cellular metabolism and the regulation of histone acetylation[1][2].

Formula: C5H9O7P

References: [1]Nemmara VV, et al. Substrate Profile of the Phosphotriesterase Homology Protein from Escherichia coli. Biochemistry. 2018 Oct 30;57(43):6219-6227./[2]Zhang JJ, et al. Nuclear dihydroxyacetone phosphate signals nutrient sufficiency and cell cycle phase to global histone acetylation. Nat Metab. 2021 Jun;3(6):859-875.

CAS Number: 2267338-53-2

Molecular Weight: 212.09

Research Area: Others

Target: mTOR

• SKU: MEXHY-171229-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-171229-0
• Package Unit: Get quote
• Quantity Unit: STK