15-LOX-1 inhibitor 2

Product Description: 15-LOX-1 inhibitor 2 (Compound 5i) is an inhibitor of 15-lipoxygenase-1 (15-LOX-1) with an IC50 of 1.7 μM. 15-LOX-1 inhibitor 2 inhibits the activity of 15-LOX-1 enzyme, reduces the production of lipid peroxides, thereby inhibiting lipid peroxidation and protecting cells from cell death induced by RSL3 (HY-100218A). 15-LOX-1 inhibitor 2 can be used in research on cell death mechanisms, oxidative stress-related diseases and other fields[1].

Formula: C22H27ClN2

References: [1]Zhang J, et al. Novel 15-lipoxygenase-1 inhibitor protects cells from RSL3-induced cell death. Eur J Med Chem. 2025 Jun 5;290:117517.

Molecular Weight: 354.92

Research Area: Inflammation/Immunology

Target: LOX-1

• SKU: MEXHY-173332-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173332-0
• Package Unit: Get quote
• Quantity Unit: STK