5'-ODMT cEt m5U Phosphoramidite (Amidite), CAS 1197033-22-9

Product Description: 5'-ODMT cEt m5U Phosphoramidite Amidite is a locked nucleic acid (LNA) analog. 5'-ODMT cEt m5U Phosphoramidite Amidite shows excellent safety and antisense activity in mice[1][2].

Applications: Cancer-programmed cell death

Formula: C42H51N4O9P

References: [1]Fiona J. Laraman, et al. Investigating the Activation Kinetics of Phosphoramidites for Oligonucleotide Synthesis. Org. Process Res. Dev. 2022, 26, 3, 764-772./[2]Vasquez G, et al. Site-specific incorporation of 5'-methyl DNA enhances the therapeutic profile of gapmer ASOs. Nucleic Acids Res. 2021 Feb 26;49(4):1828-1839.

CAS Number: 1197033-22-9

Molecular Weight: 786.85

Compound Purity: 99.25

Research Area: Cardiovascular Disease

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: Nucleoside Antimetabolite/Analog

• SKU: MEXHY-148506-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-148506-100
• Package Unit: 100 mg
• Quantity Unit: STK