α-Amylase-IN-11

Product Description: α-Amylase-IN-11 (compound C5f) is an α-Amylase inhibitor (IC50=0.56 μM) that can reduce the sugar level in vivo. α-Amylase-IN-11 has a moderate inhibitory effect on α-glucosidase (α-glucosidase), with IC50=11.03 μM. α-Amylase-IN-11 can significantly reduce the glucose concentration in a mouse model and has the potential for use in diabetes research[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C22H18N4OS

References: [1]Çapan İ, et al. Next-Generation Carbazole-Linked 1,2,4-Triazole-Thione Derivatives: Strategic Design, Synthesis, Molecular Docking, and Evaluation of Antidiabetic Potential. ACS Omega. 2024 Dec 25;10(1):848-861.

Molecular Weight: 386.47

Research Area: Metabolic Disease

Target: Amylases

• SKU: MEXHY-170796-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170796-0
• Package Unit: Get quote
• Quantity Unit: STK