AB8939, CAS 1974336-09-8

AB8939, CAS 1974336-09-8
SKU
MEXHY-171183-0
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MedChemExpress

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Product Description: AB8939 is an effective small moleculeMicrotubule/Tubulin polymerization inhibitor with anti-tumor activity (it inhibits tumor cell proliferation with an IC50 of less than 10 nM). AB8939 can effectively evade resistance mechanisms mediated by things like P-glycoprotein and myeloperoxidase. AB8939 can induce G2/M phase cell cycle arrest and apoptosis in cells[1].

Formula: C22H24N4O3

References: [1]Martine Humbert PhD, et al. Anticancer Activity of a Highly Potent Small Molecule Tubulin Polymerization Inhibitor, AB8939. Blood. Volume 134, Supplement 1, 13 November 2019, Page 2075.

CAS Number: 1974336-09-8

Molecular Weight: 392.45

Research Area: Cancer

Target: Apoptosis;Microtubule/Tubulin
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SKU MEXHY-171183-0
Manufacturer MedChemExpress
Manufacturer SKU HY-171183-0
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